Product name:2-Methylpropanethioamide

MW: 103.19
Cas No.:13515-65-6


Product use:Basic raw materials, organic intermediates, pharmaceutical intermediates

The synthetic route is as follows:

diphosphorus pentasulfide; diethyl ether; benzene;

Reactants are commercially availlable.
Yun, Weiya, US2002/161237, A1, (2002) A. 2-Methylpropanethioamide Phosphorus pentasulfide (3.25 g, 14.6 mmol) was added to a solution of 2-methylpropanamide (5.00 g, 57.4 mmol) in diethyl ether/benzene (2:1; 150 mL). The mixture was stirred for 2.5 h at room temperature to give a tacky yellow solid and a supernatant layer. The supernatant was filtered through Celite.(R). and the tacky yellow solid was extracted with diethyl ether (3*25 mL) and the extracts were filtered through Celite.(R).. The combined organic l ayers were evaporated to give 2-methylpropanethioamide (4.6 g, 78percent yield) as a yellow oil that solidified on standing.