Product name：3-FLUOROPIPERIDINE HYDROCHLORIDE
Product use：Basic raw materials, organic intermediates, pharmaceutical intermediates
The synthesis process is as follows:
hydrochlorid acid; 1,4-dioxane; dichloromethane;
Reactants can be synthesized in 1 step.
BALINT, J贸zsef, WO2015/150449, A2, (2015) To a suspension of 773 mg (3.80 mmo[) tert-buty[ (35)-3-f[uoropiperidine-1- carboxy[ate (stepl) in 45 mL dich[oromethane was added 9.5 mL (38 mmo[) 4 Mhydroch[oric acid in dioxane. The mixture stirred overnight at room temperature and was then concentrated under reduced pressure to give crude (35)-3- f[uoropiperidine hydroch[oride (531 mg) which was used in the next step without purification.