Product use：Basic raw materials, organic intermediates, pharmaceutical intermediates
The synthetic route is as follows:
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; 1,4-dioxane;
Reactants are commercially availlable.
CHAN, Katrina, US2013/53362, A1, (2013)  To a suspension of ? 5-bromo-1-ethylpyridin-2(1H)-one (250 mg, 1.23 mmol) in ? 1,4-dioxane (15 mL), 4,4,4?,4?,5,5,5?,5?-octamethyl-2,2?-bi( ? 1,3,2-dioxaborolane (346.4 mg, 1.35 mmol), ? 1 ,1?-bis(diphenyl phosphino)ferrocene]dichloropalladium(II) (100 mg, 0.12 mmol) and ? potassium ace tate (301.4 mg, 3.08 mmol) were added. The reaction mixture was stirred at reflux for 3 h. The resu lting mixture was concentrated in vacuo, and the residue was purified by column chromatography on silica gel (10-101)'0 PE-AE) to afford ? 1-ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyr idin-2(1H)-one