Product name：4-CHLOROMETHYL-2-METHYLTHIAZOLE HYDROCHLORIDE
Product use：Basic raw materials, organic intermediates, pharmaceutical intermediates
The synthesis process is as follows:
Reactants are commercially availlable.
Dong, Steven, US2003/134883, A1, (2003) EXAMPLE 16 2-methyl-4-(chloromethyl)thiazole A mixture of thioacetamide (6.9 g) and 1,3-dichloroacetone (13.4 g) in 100 mL of toluene is heated under reflux for 2 hours, then cooled to ambient temperature and washed sequentially with sat. N aHCO3 and brine. The solution is dried over MgSO4, filtered, and evaporated. The product is purified by silica gel chromatography.